The Benefits of Nicotinamide Riboside Supplementation


The Benefits of Nicotinamide Riboside Supplementation

Recent findings published in the esteemed journal Cell Reports highlight the significant benefits of Nicotinamide Riboside (NR) supplementation. This potent NAD+ precursor not only reduces inflammation in healthy individuals but also exhibits promising results in cells derived from psoriasis patients.

A Leap Forward in NAD+ Research

This groundbreaking study, supported by the ChromaDex External Research Program (CERP™), utilized ChromaDex’s patented NR ingredient, Niagen, to advance our understanding of NR’s anti-inflammatory properties. The research community, including ChromaDex CEO Rob Fried, extends heartfelt gratitude to Dr. Michael Sack of the National Institutes of Health (NIH) for his invaluable contributions to this pivotal research.

Why is NR Supplementation Essential?

NR, a superior NAD+ precursor, plays a crucial role in mitigating inflammation, a key aging indicator. Incorporating Tru Niagen into a balanced diet and regular exercise regimen can safely and effectively elevate NAD+ levels, offering a legally protected and extensively researched dietary supplement for improved aging.

Connecting the Dots: NAD+ and Inflammation

Chronic inflammation, or metaflammation, is a consistent factor in various health conditions, including autoimmune disorders and chronic diseases. Environmental and lifestyle factors, such as smoking and poor diet, can exacerbate chronic inflammation, making NR supplementation vital for maintaining optimal health.

NR: A Powerful Ally Against Inflammation

With its proven efficacy in increasing NAD+ levels, NR supplementation supports cellular processes essential for life, including energy production and DNA repair. The anti-inflammatory effects of NR are evident not only in the elderly or those with inflammation-related disorders but also in healthy individuals, providing a robust defense against inflammation.

Clinical Study Highlights

  • NR supplementation reduced immune responsiveness in both healthy volunteers and psoriasis patients.
  • NR treatment upregulated antioxidant defense pathways genes.
  • NR decreased harmful reactive oxygen species production and lipid peroxidation in CD4+ T cells.

Relevance of the Study

The promising data from studies led by Dr. Sack suggest that NR supplementation offers not only defense against inflammation for healthy individuals but also potential therapeutic applications for autoimmune disorders, pending further research confirmation.


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