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ENDECE Neural presents remyelination findings at 2013 Biotech Showcase

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Dr. James Yarger, CEO of ENDECE Neural, will discuss the company’s novel therapeutic for directly inducing remyelination of demyelinated axons to treat neurological diseases such as Multiple Sclerosis (MS). Currently there are no drugs commerciallyavailableforremyelinationinMS,oranyotherdiseaseassociatedwith demyelination.ENDECENeuralmayhaveoneofthefirstcompoundswiththeability todirectlyinduceremyelination.Thisnewtherapeuticcouldpotentiallybeusedalone or in combination with other immunosuppressant or anti-inflammatory therapies to help restore function and mobility in MS patients.

First public information service devoted to gut microbiota now online

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Gut Microbiota World Watch is a new online platform aimed at increasing knowledge and understanding of gut microbiota and its importance for health and quality of life. The intestines are populated with a universe of lifeforms called gut microbiota that perform a variety of vital functions, including functioning as part of the immune system. Launched by the Gut Microbiota and Health section of the European Society of Neurologastroenterology and Motility, this public information service will provide the latest news about gut microbiota. It will act as a point of reference for gut microbiota issues and offer information in straight-forward and easy to understand language. The composition of gut microbita is unique to each individual and evolves throughout the entire life. It is affected by external factors, including conditions of birth, diet, environment, or use of antibiotics. The information service can be accessed at gutmicrobiowatch.org.

Health Canada gives nurse practitioners more prescribing authority

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Health Canada has published new regulations to grant more prescribing authority to nurse practitioners (NPs), midwives and podiatrists. NPs are registered nurses with additional education, advanced nursing experience, and who work collaboratively with other health care providers. Current legislation and regulation authorize NPs to independently diagnose and treat health conditions, but with limited prescription authority. The new regulations allow NPs across Canada (except Yukon) to prescribe controlled substances under the federal Controlled Drug and Substances Act. This will help to provide more timely and comprehensive care to patients.

Health Canada suspends License of Chemical Testing Laboratory for falsified results

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Health Canada suspended the License of Chemi Pharmaceutical Inc. of Mississauga, Ontario after uncovering falsified testing results during the course of an inspection. As a precautionary step, companies that had testing done by Chemi Pharmaceutical are being asked to temporarily halt sales of those products until their safety can be confirmed. Health Canada has not seen any indication that the health of Canadians has been compromised.

New treatment for Obstructive Sleep Apnea available in Canada

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Ventus Medical has announced the introduction of its proprietary Provent Sleep Apnea Therapy into Canada. Provent Therapy is an innovative, non-invasive treatment for obstructive sleep apnea. This is a scientifically validated and user-friendly approach that uses nasal expiratory positive airway pressure to keep a patient’s airway open during sleep. Over 1 in 4 Canadian adults are at high risk of obstructive sleep apnea. Continuous positive airway pressure is the primary treatment, but not all patients can tolerate it as a long term treatment. Provent Therapy improved quality of sleep while reducing sleep apnea, daytime sleepiness and snoring in clinical studies in the US. It is easy to use, portable and discreet for use at home or when travelling.

Study cautions provinces about tendering generic medicines

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A new study called “Tendering generic drugs: What are the risks?” was commissioned by the Canadian Generic Pharmaceutical Assocation (CGPA). According to the study, tendering generic drugs in Canada could cause many negative consequences such as potential drug shortages because of less redundancy in the drug supply system, less manufacturing of generic drugs in Canada, less customer services offered by generic suppliers to pharmacies, the closure of some pharmacies, and others. The study discusses how tendering removes the incentive for generic pharmaceutical manufacturers to mount legal challenges to invalid or non-infringement patents on brand-name drugs. The authors argue that tendering has important implications and is only one of the approaches that can be used to procure generic drugs.

Large genetic study shows evidence of link between inflammation and heart disease

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The University of Ottawa Heart Institute participated in the largest genetic study of coronary artery disease to date. The study was published in the scientific magazine Nature. 15 genetic regions were newly associated with the disease, bringing the total to 46. The research team also identified 104 independent genetic variants that are highly likely to be associated with the disease. These discoveries have helped other doctors from the Heart Institute identify biological pathways that underlie the disease and showed that lipid metabolism and inflammation play a significant role. These findings show clear evidence that several of the genetic risk factors for coronary artery disease function through known inflammatory pathways, which could pave the way for developing new therapies.

Health experts urge Canadian women to get their PAP test

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The Federation of Medical Women of Canada and the Society of Obstetricians and Gynaecologists of Canada launched their annual campaign titled ‘National Pap Test Campaign’. Healthcare professionals across Canada took a stand against cervical cancer by hosting public Pap test clinics in their community.

Disconnect between patients and doctors over symptom burden in Ulcerative Colitis

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The results of an international survey called ‘Mind the Gap’ assessed patients’ and healthcare professionals’ differing perceptions of ulcerative colitis and were presented during the United European Gastroenterology Week. On average, patients reported almost six flare ups in the previous year while physicians reported almost four. Pain was ranked as very important for patients while physicians ranked urgency and stool frequency the highest. These key differences identified that improved communication between patients and their physician or specialist and better patient education would potentially address these issues.

Canadian surgical first to remove cancer from the liver

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At the London Health Sciences Centre, Dr. Roberto Hernandez-Alejandro completed the first of a two stage surgery to remove cancer from the liver. Formally called an associating liver partition and portal vein ligation for stage hepatectomy, or ALPPS procedure, the surgical first is that both stages of the hepatectomy, or removal of the liver, are completed in one week to ensure that cancer does not spread to other parts of the liver.

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