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No Bittersweet Kiss Goodbye for This Mistletoe Fan

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Ottawa ND Dugald Seely, executive director of the Ottawa Integrative Cancer Centre says that mistletoe – as part of an integrated treatment can be effective fighting cancer. And one of his patients, 43-year-old Susie Saghbini, strongly agrees.

Suffering from stage 4 colon cancer, Saghbini had undergone 39 chemotherapy treatments over a two year period before doctors suggested she visit the Ottawa Integrative Cancer Centre on the chance that she might find some relief from her chemo symptoms – which were so severe that Sagbini says she couldn’t look down without her nose starting to bleed. She said she was falling apart. As part of her treatment she received injections of European mistletoe extract.

Much to her surprise – and no doubt the surprise of a few doctors – her tumours began to grow smaller. There is no direct evidence that this was due to the mistletoe, but Saghbini believes it was.

Combined with chemotherapy, says Seely, “it seems to reduce symptoms like fatigue, nausea, neutropenia, some of the issues [cancer patients] commonly deal with.”

He explains that, at his clinic, mistletoe is primarily used to support the immune system and that it helps support the quality of life during chemotherapy.

While therapeutic use of mistletoe is not recognized by the American Cancer Society or by medical associations in North America, Seely insists that some trials have shown that mistletoe used alongside conventional treatments can help ease symptoms. But he also concedes that more research must be done.

Saghbini, however, demands no such evidence, happy with the fact that it has now been over a year since her last chemo. She is sure in her heart that it was the mistletoe.

US Declares War on Global Tuberculosis Epidemic

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National Institutes of Health (NIH) Awards Seven Year Grant to Tackle World Health Problem

In an effort to stop tuberculosis (TB) from becoming progressively less treatable worldwide, the NIH (the US Government’s medical research agency) has awarded Weill Cornell Medical College more than $6.2 million in first-year funding to support a research collaboration among six institutions in close alliance with voluntary pharmaceutical partners. The total funding, provided by the National Institute of Allergy and Infectious Diseases, could be up to $45.7 million over seven years.

 

TB-causing bacteria are increasingly becoming resistant to the most commonly used treatments, presenting a growing problem in a globalized world, says TB Research Unit principal investigator Dr. Carl Nathan, chair of the Department of Microbiology and Immunology at Weill Cornell. For patients who don’t respond to those drugs, the infection can require more than two years of therapy with multiple, toxic and expensive alternatives, which often fail. When TB, which is spread through the air, is not effectively treated, it is usually lethal.

 

“Neither academia nor pharma can solve this problem working alone. We have to work together to improve treatment of tuberculosis, or it will continue to spread and become even more resistant to treatment than it is today,” says Dr. Nathan.

 

Infectious disease specialist, Dr. Michael Glickman, who is serving as the TB Research Unit’s co-principal investigator, notes that TB is the single leading cause of death from bacterial infection, and the second leading cause of death from any pathogen. One in three people globally is infected with the bacteria that cause TB. In 2013, an estimated 9 million new cases of TB were reported and 1.5 million people died, according to the World Health Organization.

 

The Tuberculosis Research Unit involves two main tracks. The first addresses TB infection biology in patients, and the center of this work shifts to Haiti, where TB, including drug-resistant TB, is a major health problem.  Dr. Glickman’s group will study the expression of genes by blood cells that may provide markers of resistance to initial infection and an early indication of treatment response. He will also investigate the effect of special types of lymphocytes and the role of composition of the intestinal bacteria in resistance to infection and response to therapy.

 

The second, parallel track of the grant, led by Dr. Nathan, continues and expands ongoing efforts by investigators at Weill Cornell and other institutions who have been working with the Bill & Melinda Gates Foundation’s TB Drug Accelerator. In that program, pharmaceutical companies provide chemical compounds that academic labs test in diverse ways, seeking compounds with new mechanisms of action. The active compounds, called “hits,” must pass through a gauntlet of increasingly stringent tests, often undergoing extensive chemical modifications, before they qualify as “leads” that can be considered for later stages of drug development.

 

In this “hit-to-lead” work, researchers seek the active compounds that are most potent and least toxic, try to identify their molecular targets, and test whether their properties can be improved. In particular, Dr. Nathan’s lab tests if the compounds can kill persistent TB bacteria. These tests were developed in response to ongoing studies of TB’s biology, including its genetics and the genetics of the host response, Dr. Nathan says.

 

Through the Drug Accelerator program and related collaborations, multiple drug companies have allowed Dr. Nathan’s team to screen more than 1.3 million compounds. Such open access to company compound collections “is almost unheard of,” says Dr. Nathan, “particularly when access is granted to the same academics by several companies at once.“

Acosta Sales & Marketing to Acquire Higgins Cohn Brand Management

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Acosta Sales & Marketing to Acquire Higgins Cohn Brand Management

Acquisition broadens Natural/Specialty Sales reach in Canada

Acosta Sales & Marketing, a leading full-service sales and marketing agency in the consumer packaged goods (CPG) industry, announced it has signed a definitive agreement to acquire Higgins Cohn Brand Management,  the largest natural foods sales agency in Canada.

“Higgins Cohn is the leading natural foods agency in Canada representing many of the top natural product brands,” said Robert Hill, President & CEO of Acosta. “Higgins Cohn’s extensive experience, strong relationships and service excellence will enable us to expand our reach in the Natural/Specialty Sales channel.”

Acosta created a U.S. Natural/Specialty Sales channel in 2001 by partnering with top local and regional agencies specializing in natural and specialty foods. The team is comprised of experienced, dedicated associates who have spent their entire careers in the natural foods channel. Acosta Natural/Specialty Sales has grown to become the largest provider of integrated sales and marketing solutions to leading natural and specialty brands in every category across all retail channels.

“Our team is excited to become a part of Acosta’s culture focused on people, teamwork, trust and results,” commented Patrick Higgins, President, Higgins Cohn Brand Management. “We are aligning ourselves with experienced industry experts and providing best-in-class training opportunities for our associates. By joining forces with Acosta, we will be able to provide our clients and customers with enhanced capabilities and new resources to drive growth.”

The transaction is expected to close in March, 2015.

 

 

High Nutrition Business API

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High Nutrition Business API

On Feb 10, semantic technology company Edamam launched two new Nutrition Analysis and Recipe Search APIs, providing data-driven, cloud-based nutrition solutions for businesses in the food, health and wellness sectors.

These apps provide “real-time analysis of any recipe or ingredient list with detailed information for over 30 nutrients and nutrition claims for more than 20 major diets, such as vegan, paleo and gluten-free.”

Drawing from over 500 of the top food sites in the English web, Edamam’s Recipe Search API builds on their semantically organized database of 1.5 million nutritionally tagged and analyzed recipes and provides results for high quality recipes that fit a particular diet need or calorie requirement.

Among the current users of Edamam’s API solutions are Epicurious, Random House and Gannett.

“The Nutrition Analysis and Recipe Search APIs will open our unmatched, ground-breaking technology to a wide range of businesses at very affordable prices,” added Victor Penev, Edamam’s Founder and CEO.

https://developer.edamam.com.

Read more: http://www.digitaljournal.com/pr/2465731#ixzz3RTR67fBI

Retailers Keep Eyes on Target

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Retailers Keep Eyes on Target

If Target keeps to it’s proposed schedule of being out of Canada completely by early May, there is no shortage of companies interested in moving in.

“Canadian Tire, Costco, Walmart, Home Depot and Metro grocery stores have all expressed an interest in some of our Target locations,” said David B. Henry, vice chairman and CEO of Kimco Realty Corp. Regardless of Target’s lack of success in Canada, property values and prices remain at historic high levels here, thanks to strong demand from pension funds and other institutional investors, he says. Kimco reported strong leasing momentum across its portfolio in the fourth quarter, with leasing spreads of 9.4 percent.

Meanwhile, Canadian landlord RioCan has 26 locations currently leased by Target, representing 1.9 percent of its total annualized rental revenue, at an average lease rate of . (hotelfauchere.com) 62 per square foot and an average remaining lease term of approximately 12.7 years. Target U.S. is also guaranteeing these leases for their remaining terms.

http://www.icsc.org/sct/newswire/canadian-landlords-find-new-users-for-target-stores

 

Calgary Retail Space in High Demand

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Calgary Retail Space in High Demand

Despite the woes of the Canadian oil industry, retail vacancy rates in Calgary dropped from 2.7 per cent to 2.2 per cent this year and nearly 14 million square feet of new retail development is either being proposed or currently under construction. The report by Barclay Street Real Estate, said American retailer Target’s departure from Canada will skew the current vacancy rate, roughly doubling the total vacant space in Calgary, as an estimated 725,000 square feet of retail space will come back on the market with the closing of these stores.

Jonathan Gheron, a retail associate with Barclay Street Real Estate says, “Our economy has been thriving. There’s competition for current good space and the additions of this space I believe most of it will get absorbed.

“Overall, the consensus for Calgary is still positive. There’s still people who want to come here and open stores. The economy the way it is, is unfortunate but we haven’t seen a slowdown in retail. It’s still a very active market.” 

Herbasante Refines Taste of High DHA Omega Oil

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Herbasante Refines Taste of High DHA Omega Oil

Herbasante – a Canadian company that specializes in providing a wide range of innovative natural and non-toxic homeopathic and herbal remedies at affordable prices – has improved one of their market leading supplements to make it even better.

President Patrick Toledano tells us, “We have had an Omega oil called Neuromega for about 10 years now – it’s the highest DHA formula on the market – in terms of concentration. This week we’re launching a new flavour. We’ll still have the old Cran-Raspberry flavour but now we’re launching an orange flavor that is absolutely delicious – 2750 mg of DHA per teaspoon. It has the new orange flavour – incredibly non-fishy. Now that we’ve improved the favour it should bring this already popular product to a whole different level.”

And not only that. Herbasante’s put the Umcka back in the Bronkotux!

“One of our cough syrup flavours has Umcka – which was removed from the market awhile ago. We were able to get an NPN and we were able to bring it back. We’re very proud of that and we’ve also launched a homeopathic cough syrup for kids – with a kids dosage on the label. It’s our ability to get NPNs for these things that is really setting us apart. We can do things that others have not been able to accomplish.”

Toledano estimates that they have product in over 1000 stores from coast to coast.

 

Microwaves and Nutrients

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Maybe we shouldn’t feel guilty about that microwave oven in our kitchen. Most North American homes have them. The convenience they offer is almost irresistable. But despite the widespread use of microwave ovens and their excellent safety record, some people have lingering doubts that cooking food with microwaves somehow makes food less healthy by zapping away nutrients. Does cooking with microwaves do that?

Think about how microwaves work – cooking food using waves of energy that are similar to radio waves but shorter. These waves are remarkably selective, primarily affecting water and other molecules that are electrically asymmetrical — one end positively charged and the other negatively charged. Microwaves cause these molecules to vibrate and quickly build up thermal (heat) energy.

Some nutrients break down when they’re exposed to heat, whether it is from a microwave or a regular oven. Vitamin C is perhaps the clearest example. But because microwave cooking times are shorter, is it possible that cooking with a microwave does a better job of preserving vitamin C and other nutrients that break down when heated?

Cooking vegetables in water robs them of some of their nutritional value because nutrients leach out into the cooking water. For example, boiled broccoli loses glucosinolate, the sulfur-containing compound that may give the vegetable its cancer-fighting properties (as well as the taste that many find distinctive and some find disgusting). Steamed broccoli holds on to more glucosinolate than boiled or fried broccoli.

The cooking method that best retains nutrients is one that cooks quickly, heats food for the shortest amount of time, and uses as little liquid as possible. Microwaving meets those criteria. Using the microwave with a small amount of water essentially steams food from the inside out. That keeps more vitamins and minerals than almost any other cooking method.

But let’s not get too lost in the details. Vegetables, pretty much any way you prepare them, are good for you, and most of us don’t eat enough of them. And the microwave oven? A marvel of engineering, a miracle of convenience — and sometimes nutritionally advantageous to boot.

 

Excerpted from the Harvard Health article “Microwave Cooking and Nutrition” http://www.health.harvard.edu/staying-healthy/microwave-cooking-and-nutrition

(Re) Consider the Cranberry

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A recent peer-reviewed study, published in Nutrition Research, shows cranberry juice drinkers had lower than normal levels of C-reactive protein, a marker of inflammation, and better overall heart health. The findings bolster the broader scientific literature that’s setting cranberry juice apart as a great tasting beverage that can provide whole body benefits and be part of a healthy diet.

Using the CDC’s National Health and Nutrition Examination Survey (NHANES) data for US adults (aged 19 and older), researchers compared consumers who drink an average of about two servings of cranberry juice per day – roughly 14 fluid ounces – over two non-consecutive days with those who do not. They pooled four years’ of data to determine if there were differences between groups. Turns out that regular cranberry juice consumers did not have higher body weight or even an increased likelihood for becoming overweight. Nor did cranberry juice drinkers consume more calories than those who didn’t drink cranberry juice.

While many in the healthy living community advocate for limiting added sugars, this study positions cranberry juice as an exception to the rule and reinforce previous findings that point to cardiovascular health benefits from cranberry juice, while also underscoring a link between cranberry juice consumption and total health.

“Cranberry beverages may be inappropriately associated with contributing to increased weight or diabetes risk,” said Kiyah J. Duffey, Ph.D., Virginia Tech, first author on the paper. “In actuality, mounting evidence suggests quite the opposite. Packed with polyphenols, like flavonoids, cranberry juice may contribute to improved cardiovascular health.”

Excerpted from Business Wire article “Cranberry Juice Scores High Marks in Heart Health”

 

 

Food for Thought

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The top nutrition advisory panel in the United States has decided to drop its caution about eating cholesterol-laden food, a move that could undo almost 40 years of government warnings about its consumption.

The group’s finding that cholesterol in the diet need no longer be considered a “nutrient of concern” stands in contrast to the committee’s findings five years ago, the last time it convened. During those proceedings, as in previous years, the panel deemed the issue of excess cholesterol in the American diet a public health concern.

The finding follows an evolution of thinking among many nutritionists who now believe that, for healthy adults, eating foods high in cholesterol may not significantly affect the level of cholesterol in the blood or increase the risk of heart disease.

The greater danger in this regard, these experts believe, lies not in products such as eggs, shrimp or lobster, which are high in cholesterol, but in too many servings of foods heavy with saturated fats, such as fatty meats, whole milk, and butter.

The new view on cholesterol in food does not reverse warnings about high levels of “bad” cholesterol in the blood, which have been linked to heart disease. Moreover, some experts warned that people with particular health problems, such as diabetes, should continue to avoid cholesterol-rich diets.

While we’re all growing accustomed to conflicting dietary advice, the change on cholesterol comes from the influential US Dietary Guidelines Advisory Committee, the group that provides the scientific basis for the “Dietary Guidelines.” That federal publication has broad effects on the American diet, helping to determine the content of school lunches, affecting how food manufacturers advertise their wares, and serving as the foundation for reams of diet advice.

The problem with nutrition research is that most of it relies on large studies of populations and their dietary patterns obtained mostly through dietary questionnaires or 24-hour dietary recall. The first study linking saturated fats to heart disease by Ancel Keys (and on which 50 years of dietary policy to eat low fat was based) looked at about 30 men from Crete and their previous day’s diet and linked that to the fact they had fewer heart attacks than people from countries that ate more saturated fat. Skimpy evidence at best! In fact, most of the “evidence” that fat in general and saturated fat in particular is bad for us is being rigorously challenged by better and more specific research.

These type of studies are further complicated because it is very hard to tease out the factors that matter. For example, when Asians move from Asia to the U.S., they eat more meat and have more heart disease and cancer, but they also consume far more sugar. So it is the meat or is it the sugar? Hard to know.  These types of population studies also cannot prove cause and effect, only show correlation. Yet, the media and consumers take it as gospel. We thought dietary cholesterol was bad and were told to avoid egg yolks at all costs. Turns out they appear to have no impact on cholesterol.

Many experimental studies on vegan or paleo diets, which should give more direct evidence of cause and effect often have only small numbers of people in the study, making it hard to draw firm conclusions.  Even worse is that the diets they use for comparison (the control group) are not ideal alternative diets. Comparing a vegan diet of chips and Coke, bagels and pasta to a paleo diet of healthy veggies and grass fed meat won’t be very helpful, nor would comparing a paleo diet of feedlot meat, bologna and no fresh veggies to a whole foods, low glycemic vegan diet.

Also, eating a low fat versus a high fat vegan diet has very different health benefits. The Eco-Atkins or high fat, high protein, low carb, low glycemic vegan diet performs better for weight loss and cholesterol lowering than a low fat vegan diet that avoids nuts, seeds and avacados.

RD Laing said that “scientists can’t see the way they see, with their way of seeing.”

Let’s focus take a close look at what is in common between paleo and vegan (healthy vegan), because there is more that intelligent eating has in common than there are differences. They both focus on real, whole, fresh food that is sustainably raised.

Here are the characteristics of a healthy diet everyone agrees on:

  1. Very low glycemic load — low in sugar, flour and refined carbohydrates of all kinds.
  2. High in vegetables and fruits. The deeper the colors, the more variety, the better. This provides a high phytonutrient content protective against most diseases. (Although the paleo camp recommends lower glycemic fruit such as berries.)
  3. Low in pesticides, antibiotics and hormones and probably no or low GMO foods.
  4. No chemicals, additives, preservatives, dyes, MSG, artificial sweeteners and other “Franken Chemicals” that you would never have in your pantry.
  5. Higher in good quality fats — omega 3 fats for all. And most camps advise good quality fats from olive oil, nuts, seeds and avocados. Although some still advise very low fat diets for heart disease reversal.
  6. Adequate protein for appetite control and muscle synthesis, especially in the elderly.
  7. Ideally organic, local and fresh foods should be the majority of your diet.
  8. If animal products are consumed they should be sustainably raised or grass fed.
  9. If you are eating fish you should choose low mercury and low toxin containing fish such as sardines, herring and anchovies or other small fish and avoid tuna, swordfish and Chilean sea bass because of the high mercury load.

Excerpted from the article “Why You Should Be Paleo-Vegan” by Dr. Mark Hyman