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Santa Cruz Group acquires Life Science Nutritionals

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Vitality hires new directors at the annual general meeting

On Tuesday, June 30th, Life Science Nutritionals was sold to Santa Cruz Nutritionals, one of the leading suppliers of confection-based nutritional delivery.

As Canada’s only manufacturer of vitamin gummies, Life Science adds a “great portfolio of brands including IronKids and Adult Essentials” as well as “innovative and different technology in the gummy space” to Santa Cruz Nutritionals, says Rob Lewis, previous vice-president of sales for Life Science.


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Founded in 2005 by Stuart Lowther, Life Science is dedicated to developing nutritional products with unparalleled quality that benefit the health of all consumers. The corporation was recently named the second fastest growing company on the Canadian 2014 Profit 500 ranking.

Claude Daigneault of the Jean Coutu Group Inc. retires

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Claude Daigneault of the Jean Coutu Group Inc. retires

Claude Daigneault of The Jean Coutu Group (PJC) Inc., has retired from his position as buyer last Friday, July 3rd. Marie Christine Roy has taken over as his replacement.


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The Jean Coutu Group is one of the most trusted names in Canadian pharmacy retailing, operating out of 416 franchised stores in Quebec, New Brunswick and Ontario. For more information on the business, visit their company website.

A new role for zebrafish: larger scale gene function studies

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A relatively new method of targeting specific DNA sequences in zebrafish could dramatically accelerate the discovery of gene function and the identification of disease genes in humans, according to scientists at the National Human Genome Research Institute (NHGRI), part of the National Institutes of Health.

 

In a study posted online on June 5, 2015, and to be published in the July 2015 issue of Genome Research, the researchers reported that the gene-editing technology known as CRISPR/Cas9 is six times more effective than other techniques at homing in on target genes and inserting or deleting specific sequences. The study also demonstrated that the CRISPR/Cas9 method can be used in a “multiplexed” fashion – that is, targeting and mutating multiple genes at the same time to determine their functions.

 

“It was shown about a year ago that CRISPR can knock out a gene quickly,” said Shawn Burgess, Ph.D., a senior investigator with NHGRI’s Translational and Functional Genomics Branch and head of the Developmental Genomics Section. “What we have done is to establish an entire pipeline for knocking out many genes and testing their function quickly in a vertebrate model.” Researchers often try to determine the role of a gene by knocking it out – turning it off or removing it – and watching the potential effects on an organism lacking it.

 

Such larger scale – termed high-throughput – gene targeting in an animal model could be particularly useful for human genomic research. Only 10 to 20 per cent of recognized human genes have been subjected to such rigorous testing, Dr. Burgess said. The functions of many other genes have been inferred based on analyzing proteins or have been identified as possible disease genes, but the functions of those genes have not been confirmed by knocking them out in animal models and seeing what happens.

 

“This is a way to do that on a more cost-efficient and large scale,” Dr. Burgess said.

 

“The study of zebrafish has already led to advances in our understanding of cancer and other human diseases,” said NHGRI Director Eric Green, M.D., Ph.D. “We anticipate that the techniques developed by NHGRI researchers will accelerate understanding the biological function of specific genes and the role they play in human genetic diseases.”

 

The CRISPR/Cas9 method of gene editing is one of the two essential components in the NHGRI team’s high-throughput method. Modeled on a defense mechanism evolved by bacteria against viruses, CRISPR/Cas9 activity was first described in 2012. Since then, its use has spread quickly in genomic research labs in the United States and abroad.

 

The acronym CRISPR stands for “clustered, regularly interspaced, short palindromic repeat,” referring to a pattern of DNA sequences that appears frequently in bacterial DNA. Scientists believe the CRISPR sequences reflect evolutionary responses to past viral attacks.

 

The Cas9 protein is a nuclease, an enzyme that snips a stretch of DNA in two places, in effect cutting out a piece. Bound together, CRISPR/Cas9 becomes a powerful research tool that permits researchers to target and delete a particular sequence or to insert a new sequence into the DNA of animal-model embryos.

 

The other essential component of the NHGRI team’s method is the zebrafish. The zebrafish and the mouse are the most commonly studied vertebrate laboratory animals whose genomes have been completely sequenced. The zebrafish is better suited to larger scale gene editing because about 70 per cent of zebrafish genes appear to have human counterparts and the fish are far less costly to maintain than are mice. They multiply astonishingly quickly; a female may produce as many as 200 eggs at one time. And the embryos are fertilized externally and are transparent, making them readily accessible to researchers.

 

To demonstrate the feasibility of high throughput editing, the researchers targeted 162 locations in 83 zebrafish genes – about 50 of which are similar to human genes involved in deafness. (Hearing is one of the other interests of Dr. Burgess’s lab.) This produced mutations in 82 of the 83 genes.

 

In screening embryos by fluorescent polymerase chain reaction (a technology that allows researchers to produce millions of copies of a specific DNA sequence) and high-throughput DNA sequencing, the researchers determined that overall, mutations were passed on to the next generation in 28 per cent of cases. The transmission rate was higher for some genes than for others, but in most cases, screening offspring from parent fish should be enough to spot most mutations, the researchers reported.

 

The results demonstrated that using the CRISPR/Cas9 technique in zebrafish will make it possible to both generate mutants for all genes in the zebrafish genome and carry out large-scale phenotyping, they noted in the Genome Research paper.

 

The CRISPR/Cas9 methodology works in mice, too, but it is more costly and takes far longer. Although mice actually reach sexual maturity earlier than zebrafish, they produce far fewer offspring.

 

Ultimately, Dr. Burgess hopes that his lab will use the new method to knock out about 10 per cent of the zebrafish’s roughly 25,000 genes, and he would like to see an even broader effort. “We’ve shown that with relatively moderate resources, you can analyze hundreds of genes,” Dr. Burgess said. “On the scale of big science, you could target every gene in the genome with what would be a relatively modest scientific investment in the low tens of millions of dollars.”

 

Coauthors of the Genome Research paper with Dr. Burgess were: Gaurav Varshney, Ph.D., Wuhong Pei, Ph.D., Matthew LaFave, Ph.D., Lisha Xu, M.S., Viviana Gallardo Mendieta, Ph.D., Blake Carrington, M.S., Kevin Bishop, M.S, Mary Pat Jones, M.S, Ursula Harper, M.S, and Raman Sood, Ph.D, all of NHGRI; Mingyu Li , Ph.D, and Wenbiao Chen, Ph.D, both of Vanderbilt University School of Medicine in Nashville; Sunny Huang, B.S, formerly of NHGRI, now of the University of Iowa in Iowa City; Jennifer Idol, M.S., formerly of NHGRI, now of the Jackson Laboratory in Bar Harbor, Maine; and Johan Ledin, Ph.D., of Uppsala University in Uppsala, Sweden.

Loblaw spots demand for more diverse international products

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Loblaw spots demand for more diverse international products

In a bid to reposition the path of its business, Loblaw has opened a rebranded pilot store in Mississauga, Ontario. The new store puts more emphasis on international beauty and personal care products, taking shifting consumer demographics into account.

In recent years, Loblaw’s acquisitions have helped the retailer to reach a more diverse group of consumers. To achieve this, the company purchased T&T, a supermarket chain serving Asian-Canadians, as well as Arz Fine Foods, which specializes in Mediterranean groceries.


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The new store in Mississauga will feature many successful brands that are already sold at Arz and T&T in order to cater to a more diverse clientele. To add to this, Loblaw will also sell a variety of highly sought-after Asian beauty products.

“Retail is as much about evolution as anything,” says Andrew Iacobucci, president of the discount division of Loblaw. “If you stay in any one place for too long, you’ll be overtaken.”

Burt’s Bees mourns the loss of co-founder Burt Shavitz

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Burt’s Bees mourns the loss of co-founder Burt Shavitz

Burt Shavitz, the co-founder of Burt’s Bees, passed away on July 5 at the age of 80. According to a spokeswoman for the company, the reclusive beekeeper died of respiratory complications in Bangor, Maine, surrounded by his family and friends.

Shavitz, who also acted as the face of the natural cosmetics label, began the company with Roxanne Quimby in the 1980s. He was making a living by selling his honey when he met Quimby, a single mother and back-to-the-lander. She began to make products from his beeswax, and Burt’s Bees was born.


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Their partnership ended after Quimby moved the operation to North Carolina in 1994. As the company continued to expand, Shavitz moved back to Maine, eventually leaving the business. In 2007, Clorox purchased Burt’s Bees for $925 million.

Although he is known for hailing from the backwoods of Maine, Shavitz grew up near New York, served in the Army in Germany and shot photos for Time-Life before leaving the city. In recent years, he lived in a cluttered house with no running water.

“Burt was a complex man who sought a simple life in pace with the seasons of nature on his land,” the company said in a statement. “If there is one thing we will remember from Burt’s life, in our fast-paced, high-tech culture, it’s to never lose sight of our relationship with nature.”

Zentai Wellness Centre: Taking care of your whole body

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Ten years ago, a team of naturopathic doctors, Dr. Makoto Trotter and Dr. Aileen Lim-Trotter, husband and wife, bought some commercial property at the intersection of Carlton and Jarvis streets in Toronto and Zentai Wellness Centre was open for business.

As with any newly established practice, there were a number of challenges to face. Being on the third floor of a commercial building meant no storefront presence and little walk-in traffic. To introduce their business, during the first several years after the clinic opened, Dr. Trotter and his wife spent every spare hour, evening and weekend giving free talks, handing out flyers, attending community events, hosting open house events at the clinic and networking.

In addition to dedicating all her time to Zentai, Dr. Lim-Trotter took time off as a practitioner for the first year to work as office manager instead.

“Having a naturopathic doctor/clinic owner answer every phone call and answer questions helped turn almost every open inquiry into a confirmed appointment at the clinic,” Dr. Trotter says. “It also helped streamline what we wanted and needed from an office manager since we personally were able to experience this role.”

Currently, the 1,400 square-foot clinic offers naturopathic medicine, acupuncture, pediatrics, digestive health, naturopathic dermatology, registered massage therapy, child psychology and psychotherapy. The clinic also offers lab tests and has a dispensary.

Zen-Tai Clinic 33

 

“We wanted to create an integrative clinic with naturopathic medicine at the core of a qualified, licensed wellness team that matched our philosophies. And we wanted to offer these services in a space that had a Zen, yet professional atmosphere,” Dr. Trotter says.

The clinic’s name originates from Japanese. The character “zen” means “whole” and “tai” stands for “body.” Dr. Trotter emphasizes that no matter what their patient’s concern is, their goal and philosophy is to help them become healthier as a whole.

Dr. Trotter holds an honours Bachelor of Science degree in biochemistry-biotechnology and his wife – a Bachelor of Science degree in biological sciences. Both of them are licensed naturopathic doctors. Dr. Lim-Trotter focuses on dermatology and pediatrics. She helps both adults and children with eczema, rosacea, acne and food allergies. Dr. Trotter specializes in digestion and hormonal health. He sees many patients who suffer from irritable bowel syndrome and inflammatory bowel disease, menstrual irregularities, menopause, andropause and fertility issues. Dr. Trotter says because most tests are usually quite expensive and patients have budgets, he often starts with looking into his patient’s diet first, adjusting it, analyzing the progress and then, he recommends relevant testing if required.

“Nutrition is always the foundation – whether it’s a hormonal or digestive health concern, we always start with a diet,” says Dr. Trotter. “Sometimes hormonal issues may be resolved by making diet changes before we need to pursue further testing.”

Dietary changes are also necessary for patients with food allergies. In addition to allergy testing, Dr. Trotter may also recommend a hypoallergenic diet. Although there is a lot of information online on how patients can improve their health concerns through diet, Dr. Trotter believes people need professional help to find an individualized and “realistic diet” that they can incorporate into their busy life styles.

Dr. Trotter also sees patients with fertility problems. While a number of them have some underlying health issues, including hormonal ones, for many patients, “it’s just a technicality of timing and understanding when you are fertile.”

“Of course, we try to rule things out whether it’s sperm, ovulation or hormonal issues. There may be something underlying, but a lot of times, it might just be the fact the person is not tracking their cycle properly.”

While many women use a variety of mobile apps to track their periods, Dr. Trotter also gets them to track symptoms, such as cervical mucus, spotting and basal body temperature, which helps determine the best time to conceive.

Zen-Tai Clinic 68Dr. Trotter and Dr. Lim-Trotter have created a work culture that aims at providing best care to their patients. The Zentai team currently consists of two office managers as well as a doctor with a PhD in child psychology who specializes in the assessment and treatment of children with autism spectrum disorders. There is also a registered massage therapist with a background in athletics and a psychotherapist who has a focus on wellness assessments. While their treatment rooms are now continuously full, Zentai would expand their practitioner team if someone fits the current team and philosophy.

Dr. Trotter says they have created their team by patiently searching for qualified, skilled practitioners who also have great interpersonal skills.

“We also choose practitioners who are responsive. It is all too common for professionals to not take the few minutes to reply to their clients’ queries when they need simple reassurances or clarifications. This ensures the high quality of service that we all strive to provide to our clients at Zentai, particularly in a time when communication is so accessible.”

Dr. Trotter says their team is interested in wellness in general and that conversations about vegan diets, popular health trends and organic farming are only a few of the topics the staff discuss during their day.

“We encourage our health practitioners to meet and discuss how their practices and therapy can help benefit other patients of the clinic and keep up with continuing education and share knowledge with one another,” Dr. Trotter says.

Zen-Tai Clinic 20Now, ten years after Zentai first opened its doors, Dr. Trotter still attends the same networking group that meets weekly and passes referrals to one another. He is also a health expert on CP24 as well as recently being the author of two books.

 

Dr.Trotter says that public interest in naturopathic medicine has increased over the past 10 years and more Canadians are now seeking out naturopathic doctors to be a part of their health care team. As a result, extended health insurance plans have improved their coverage for naturopathic medicine.

With current success, Zentai continues to look forward. Dr. Trotter says they are continually researching new lab tests and products to provide quality care to their clients – both current and future.

“When starting our clinic, we hoped to build a wellness team that was qualified and passionate about their work. Today, we are fortunate to have put together our ideal team at Zentai Wellness Centre and we are eager to continue spreading the word about proactive integrated healthcare.”

Zentai Wellness Centre team:
Makoto Trotter, BSc(Hons) ND
Aileen Lim-Trotter, BSc ND
Dr. Julia Broeking PhD, C.Psych
Vaishali Patel, MS EdS CCC
Colin Baird, RMT, BScKin – Registered Massage Therapist
Lily Phan and Maria Karmela Salanga – office managers

 

Giving New Life To Your Clinic

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Have you decided to bring new life to your clinic? What is it that you want to change? Most importantly, do you know your patients well enough to understand their needs and create the environment of care and peace that they are seeking?

 

We interviewed Aaron Cheng, founder and principal at C & Partners Architects in Toronto, and Lekshmy Parameswaran, partner and director of insights and strategy at fuelfor Healthcare Innovation Design and Consulting in Barcelona to get their opinions on how you can take your clinic’s design to the new heights.

 

C & Partners Architects is an architectural firm with offices in Toronto and Braga, Portugal, that creates innovative and forward-thinking design solutions for healthcare practitioners, focusing on patient experience and delivery of care. Their projects include but are not limited to SickKids Hospital Boomerang Centre in Vaughan, Ontario, and facility planning at St. Michael’s Hospital in Toronto. Fuelfor Healthcare Innovation Design and Consulting, with their offices in Spain and Singapore, and clients in and around Europe, has completed projects in the US and is currently helping the Singapore government transform patient experiences in their health system.

 

“Healthcare has such a complexity within it that it’s quite understandable people get lost somehow in that system,” Parameswaran says. “Experiences for patients, for their families and also for the staff that work in health services can be very challenging, uncomfortable and stressful. At the same time, health is a fundamental and deeply personal thing, so it really should not be this way.”

 

Cheng agrees saying that the healthcare design needs a special approach as it is the only type of design that caters exclusively to people who don’t feel well – who are nervous, emotional and in pain.

 

Many doctors willing to design or redesign their clinics are giving a lot of attention to the overall flow, layout and service quality, overlooking a number of important things. According to Parameswaran, the most common mistake that healthcare professionals usually make is designing their clinics “from inside out” – based on what they already know and what they would like to offer, rather than listening to their patients, understanding their journeys and providing a consistent quality experience.

 

“Satisfaction is the difference between expectation and perception: the more you meet the expectation, the more satisfied you can make someone. But you need to know what their expectations are. As a design team, we try to zoom out and understand how expectations are set.”

 

Parameswaran also notes that when designing a clinic, doctors sometimes forget to consider how their patients interact with the space. The reception area serves as a perfect example, she says. Oftentimes, even though the counter’s height is according to all regulations and policies, the human interaction this design detail prompts has not been considered and the patient can’t see the receptionist when they approach the counter – something fuelfor sees in different countries and health systems.

 

According to Cheng, many clients approach their clinics’ design the same way they would approach aesthetic changes in their homes, choosing materials or fixtures that look good at home but don’t last in the clinic. He often notices mistakes with mechanical and plumbing designs, which are not flexible enough to accommodate future changes or introduce new healthcare services as well as a poorly executed space planning, which usually results in not having enough storage. Some clients also cut corners on sound insulation between the treatment rooms, which doesn’t create that critical environment of privacy for the patients.

 

Fortunately, technology and modern interior design opens new opportunities for creativity and gives tons of ideas on how you can meet your patients’ expectations when it comes to your clinic’s design.

 

“Healthcare interior design changes along with the public perception of healthcare and the evolution of healthcare services,” says Cheng. According to him, most clinics now choose individual seating in their waiting rooms, the one that has a soft surface, is ergonomically designed, easy to clean and maintain, and doesn’t take up lots of space. “Like in other disciplines of design, the challenge is always to find some furniture that looks good, fits in our floor plans, is comfortable and of a reasonable price.”

 

While interior designers can work with a whole range of colours, according to Cheng, they usually avoid black and red, as they symbolize blood, danger and even death. He recommends combining them with other colours, which will allow you to create a pleasing or even luxurious environment. Appropriate colour schemes in combination with proper lighting and material textures can craft an impeccable interior design.

 

“Usually, we recommend a combination of colours together with different textures and proper lighting to create a warm and comfortable environment,” Cheng says. “Depending on the site condition of the medical facility (heritage building, retail level of a condominium, commercial high-rise or a typical medical building), we could have some greyish natural stone with stainless steel details and high gloss white panels, or orange red brick veneers with wood planks and painted steel to create a different effect.”

 

According to Cheng, interior design for treatment rooms will always depend on the doctor’s and their patients’ requirements.

 

“A typical family doctor treatment room, an ophthalmologist room or a pediatric exam room will have different requirements. The rule is to be creative while understanding the function of the rooms, the budget and the requirement of the health practitioners and patients.”

 

Parameswaran recommends stepping into your patients’ shoes, understanding your patients’ needs in context, thinking holistically of what they are going through at different stages of their healthcare journeys and translating these insights into specific design solutions that can deliver the right experience.

 

large seatingweb“At a certain stage, you need different communication tools or service scripts, you need to rethink the way you lay out the space, you need to think about interior design elements, furniture, lighting, etc.,” Parameswaran says.

 

To craft a smart design strategy, she recommends determining the pain points to understand how they affect the current experience. Oftentimes, this means “shadowing the patients” – spending time with them in a clinic and accompanying them as they go through certain services, while working with staff members to determine their challenges and concerns. This will help you see where you can intervene and what changes you can make to improve the service. Parameswaran recommends working more systematically on how you design your clinic and collaborating with the people who know how the clinic functions and what it feels like on a day-to-day basis.

 

Parameswaran agrees that clinics should definitely focus on the capabilities and the skills of their doctors, but at the same time, zooming out and understanding the patient’s point of view will add value, differentiate the service you are offering and help you craft a clinic experience that really makes sense.

 

“It can make a real difference to people’s experience if there’s consideration on the interior design level because that’s the landscape in which the action happens. So if you set the scene appropriately, you can already tackle a number of anxieties, issues and pain points for people even before you begin service delivery.”

 

CPhA urges government to update HPV immunization strategy

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CPhA urges government to update HPV immunization strategy

The Canadian Pharmacists Association (CPhA) has advised the federal government to enhance its national immunization strategy. This call to action comes at a time when a lack of access to HPV vaccination programs for young men in Canada is needlessly putting the health of Canadians at risk.

HPV is the most common sexually transmitted disease in Canada, with approximately three out of every four sexually active Canadians becoming infected with it at some point in their lives. This ailment causes five per cent of all cancers worldwide, and about 70 per cent of all cervical cancer cases, accounting for around 400 deaths per year in Canada.


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In its March 2007 budget, the federal government provided $300 million to the provinces and territories in support of a national HPV vaccination program for young women. However, few provinces in the country offer this protection to young men. Because of this, the CPhA will be heavily advocating the enhancement of Canada’s National Immunization Strategy in the upcoming federal election.

“Infectious diseases, such as HPV, continue to pose a significant threat to the health of Canadians,” says Carlo Berardi, chair of the CPhA. “Immunization is the safest, most effective way to prevent, control and eliminate vaccine-preventable diseases. The evidence is clear: vaccination saves lives.”

Can Autism Risk Be Detected Just Days After Birth?

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New research in the American Journal of Occupational Therapy examines relationships among neonatal visual and auditory responses, social behaviors, and autism risk.

 

Research conducted by a team of occupational therapists and physicians at Washington University in St. Louis aims to help detect signs of autism and altered development earlier in life, so that services can be offered sooner to improve children’s adaptive skills and outcome.

 

The team evaluated and observed 62 pre-term infants initially hospitalized at St. Louis Children’s Hospital. Early neonatal neurobehavioral testing was conducted at the infant’s due date (the time when the infant would have been born if not born early and typically the age that the infant is discharged from the neonatal intensive care unit). This included observations about social interaction, visual and auditory responses. Participants were assessed again when they were two years old with the Modified Checklist for Autism in Toddlers, and they also underwent standardized developmental testing with the Bayley Scales of Infant and Toddler Development, 3rd Edition. Children identified in this study were not diagnosed with autism, but a screening tool indicated they were at higher risk for autism.

 

“We expected to see avoidance of social interaction among infants who later screened positive for autism risk, as avoidance of social interaction and failure to make eye contact are often seen in children with autism,” says Roberta Pineda, PhD, OTR/L, assistant professor of the Program in Occupational Therapy, Department of Pediatrics, School of Medicine at Washington University in St. Louis. “Instead, our findings did not support our hypothesis, and positive screening for autism risk was associated with absence of gaze aversion in the neonatal period. In fact, infants who avoided visual interaction through gaze aversion in the neonatal period were five times more likely to have good outcome at age two years. While this was an unexpected finding, pre-term infants in the NICU may avert their gaze to protect themselves from stimuli that is too intense, and infants who later went on to screen positive for autism risk did not demonstrate this same gaze aversion response as their peers. This is, however, a different pattern from what is observed later when children with autism are more likely to avoid social interaction.”

 

The team identified that infants with later autism risk as well as poor developmental outcome were less likely to demonstrate gaze aversion and less likely to demonstrate end-point nystagmus in the neonatal period.

 

 

Teens 101 to Help Young Canadians Get Back on Track

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ThinkstockPhotos-478770342Canamedia, an independent production company, is producing Teens 101 – interactive, multimedia, multi-platform program aimed at informing and supporting youth and their families facing life challenges. Comprising of a television series, in-class lesson plans and mobile and web support systems, the program’s topics focus on youth mental health and well-being issues, such as peer pressure, bullying, family dynamics, addictions, body image, depression and anxiety.

 

Teens 101 is a great way to encourage teens and young adults to think about their overall wellness,” says Radhika Subramanyan, chief executive officer of the Canadian Mental Health Association, Halton Region Branch. “Realizing that they are not alone in facing stress and challenges and knowing how and when to seek out support is key to them developing into mentally healthy adults. We are proud to work with Canamedia on this important project.”

 

“I want to produce this show that conveys to teens, that no matter what stressful challenges they may be facing, they’re not alone,” says Daniel D’Or, producer and director of the 13-episode television series.

 

Teens 101 combines dramatic recreations with intimate, anecdotal interviews from youth and their families with each story depicting how individuals struggling through their experiences found a way get back on track.

 

Classroom lesson plans will be designed by the parent corporation of Canamedia and Teens 101 Inc., Magic Lantern Media Inc. who currently provides curriculum-correlated media to schools across Canada.

 

“The program designs for our social media and web interactive campaigns are courageous and raw with our direct ‘teen-to-teen’ approach,” says digital producer Brad Schroeder. “By utilizing a multitude of dynamic technologies we endeavour to engage today’s youth by communicating through mediums youth will connect with and understand.”