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How blocking fat transport could lead to longer life

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Humans—as well as animals and other species—have always had an on-again/off-again relationship with lipids and fats. Cholesterol, for example, is essential for health, but too much of it, can lead to death. New research from Brown University reinforces how this might be true.
While working on nematodes and mice, researchers discovered a naturally occurring protein that moves fats such as cholesterol around the body also compromises essential functions in cells that extends life.

However, the study also shows that nematodes lived up to 40 percent longer when Brown University researchers genetically blocked production of the worms’ yolk lipoprotein, known as vitellogenin (VIT).

“Protein [known as apolipoprotein B (apoB)], which has an ortholog [genes inherited from ancestors] in humans, is a major decider of what happens to fat inside intestinal cells,” said Louis Lapierre, assistant professor of molecular biology, cell biology and biochemistry at Brown University and senior author of the study in the journal Autophagy. “If you reduce the production of these lipoproteins, you allow the fat to be reused in different ways.”

Exercise at young age can lead to better long-term health

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The human gut has over 100 trillion microorganisms, and, according to a recent study published in Immunology and Cell Biology, exercising at a young age can change this microbial community to promote a healthier brain and metabolic activity over a person’s lifetime.

The research, conducted by the University of Colorado Boulder, shows that a window of opportunity exists during early human development to improve health over the long term.
Science Daily published the following quote from Monika Fleshner, the senior author of the new study and a professor in CU-Boulder’s Department of Integrative Physiology: “Exercise affects many aspects of health, both metabolic and mental, and people are only now starting to look at the plasticity of these gut microbes. That is one of the novel aspects of this research.”

Complete model describing serotonin’s role now available

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A recent study, published in the online version of The Journal of Neurophysiology, has unveiled the first complete model that details the role of serotonin in brain development and structure. The goal for researchers at the Case Western Reserve University School of Medicine was to close the existing knowledge gap on role of serotonin in the brain cortex—especially as it pertains to brain circuitry, electrical activity and function.

“For the first time, we can provide a complete description of an animal model from genes to behavior—including at the level of neuronal network activity, which has been ignored in most studies to date,” said Roberto Fernández Galán, PhD, Assistant Professor in the Department of Neurosciences at Case Western Reserve University School of Medicine.

Serotonin, also known as 5-hydroxytryptamine [5-HT], is a vital neuromodulator of brain development as well as the structure and function of neuronal (nerve cell) circuits.

General Mills acquires Epic Provisions

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General Mills acquires Epic Provisions

Food manufacturer General Mills continues to expand its natural and organic offerings by acquiring Epic Provisions, a rapidly growing, premium meat snacks company.

Epic Provisions will operate as a unit of Annie’s, a natural food brand that General Mills acquired in 2014. “The acquisition of Epic Provisions positions General Mills for exciting growth with a highly authentic brand in an entirely new natural snacking category,” said John Foraker, President of Annie’s.

Natural Markets closes stores, prepares to open others

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Natural Markets closes stores

Natural Markets Food Group, the parent company of the Mrs. Green’s and Planet Organic chains, is opening two new stores mid-January in Illinois and Alberta. The company closed two stores last month in New York State.

According to Supermarket News, store openings and closures are part of the chain’s ongoing modernization and rebranding efforts. No further closures are currently expected. Rebranding includes a new logo for Mrs. Green’s stores as well as more emphasis on locally sourced produce and products.

Life Choice adds two members to its management team

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Life Choice adds two members to its management team

Life Choice Ltd, a natural medicine company, has added two new members to its management team.

Dr. Emmanuel Mbobda, is Life Choice’s new Chief Marketing and Sales Officer, and Shawn Zemla, is the company’s new BC Sales Manager, excluding Vancouver Island.

Dr. Mbobda has worked in marketing and business development for over 12 years. His most recent employment position was with AOR Inc., as their Export Manager. Also, Dr. Mbobda has a degree in Pharmacy, and a major in Pharmacology and Pharmacognosy from the University of Perugia Italy.

Shawn Zemla’s has an education in holistic nutrition extending to whole food nutrition and food science. Shawn has several years of sales and marketing experience. His most recent position was with AOR Inc. as their territory sales manager.

Thrive Market debuts new products

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Thrive Market debuts new products

Thrive Market, an online natural and organic foods retailer, is creating its own private label products. The plan is to sell these products exclusively on Thrive’s website and not to retailers such as Whole Foods.

So far, Thrive Market has launched their own brand of organic tomato sauce and coconut oil. However, Nick Green, co-CEO of Thrive, told Fortune that the online food retailer plans to release 100 private label products in the first half of 2016.

Thrive Market wants to offer natural and organic products at prices comparable to conventional non-organic retailers. The company would price the items to cover company expenses and profits as well as shipping costs. Currently, Thrive Market makes money by offering its customers subscriptions.

“It’s Whole Foods-type products at Costco-like prices,” Green told Fortune.

Study: Vitamin D could treat MS in the future

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Study: Vitamin D could treat MS in the future

New research from the University of Cambridge in England shows that Vitamin D may help repair damage to myelin—the protective sheath surrounding nerve fibres—in people with multiple sclerosis (MS).

The study, published recently in the Journal of Cell Biology, provides considerable evidence that Vitamin D could eventually become a treatment option for patients with MS.

Research from the MS Society Cambridge Centre for Myelin Repairs shows that existing protein, known as the RXR receptor, connects to the Vitamin D receptor, which—as previously proven—helps to repair myelin.

Additional research is necessary to determine if lab results are effective in MS patients during clinical trials.

Roughly, 100,000 people living in Canada have multiple sclerosis. The Vitamin D Society, a Canadian non-profit group organization, encourages Canadians to protect their health by having their vitamin D levels tested on an annual basis.

Vitality releases report for third quarter

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In its third quarter, Vitality Products Inc. reports it is now sold in 240 independent retailers in Western Canada (up from 130 at this time last year) and increased sales 105 per cent.

However, in its third quarter, Vitality Products Inc., a natural health products company, reports a net loss of $44,738 compared to a net loss of $36,487 for the same period last year. The financial losses are primarily due to the company’s marketing efforts to build consumer awareness of the new line.

Vitality Products Inc. has 92 Natural Product Numbers (NPNs) and continues to search for business opportunities to market and license its health products and on its website, www.vitality.ca.

Nud Fud partners with iLevel Management

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United Natural Foods is buying Haddon House

Nud Fud Inc. is expanding nationally and has recently announced a partnership with iLevel Management Inc. to support that expansion.

Nud Fud Inc, a manufacturer of hand-made healthy, innovative, organic, raw, and gluten-free snacks, has recruited iLevel Management to help facilitate the company’s next level of growth. iLevel Management works together with companies who have innovative products to execute long-term plans for success.