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Chinese herb could aid in cancer treatment

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Researchers out of UCLA have found a Chinese herbal regimen that they believe could treat blood cell deficiency and cancer. The substance, known as TSY-1 (Tianshengyuan-1), increased telomerase activity in normal blood cells but decreased it in cancer cells. Telomerase is an enzyme responsible for the production of telomeres, which aid in the regulation of normal cell division.

More than 80 per cent of cancers have increased telomerase activity. Many other medical conditions are also associated with decreased or abnormal telomerase function. The ability to alter telomerase activity has important implications for treating cancers in which low numbers of blood cells are produced. When a person’s bone marrow is unable to keep up with the need for healthy blood cells, bone marrow failure is triggered.

TSY-1 has been used in China for many years to treat aplastic anemia, a condition in which the body stops producing enough new blood cells.

The five-year study, led by UCLA Jonsson Comprehensive Cancer Center member Dr. Jianyu Rao, measured the ability of TSY-1 to affect telomerase activity in cancer cells lines. The results showed that the target of TSY-1 activity is the TERT gene. TERT is the major regulatory component of telomerase activity.

Safe exercise guidelines published for diabetes patients

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An international team of clinicians and researchers has published a set of exercising guidelines for those with type 1 diabetes.

“Regular exercise can help individuals with diabetes to achieve their blood lipid, body composition, fitness and blood sugar goals, but for people living with type 1 diabetes, the fear of hypoglycemia, loss of glycemic control, and inadequate knowledge around exercise management are major barriers,” says York University Professor Michael Riddell leader of the study. “This is a big struggle for both type 1 diabetes patients and their healthcare providers. This first ever set of consensus guidelines from leading experts will help them.”

Riddell notes that patients with type 1 diabetes have to monitor their blood glucose levels before, during and after exercise.

“Regular exercise helps patients achieve a number of goals. In pediatric patients in particular, it reduces the cardiovascular disease risk profile, improves the sense of well-being and brings down average blood glucose levels (glycated hemoglobin),” adds Riddell.

In adults, both diabetic eye disease and kidney disease are less common in those who are more physically active. According to the report, those individuals also have a better chance of achieving target levels of glycated hemoglobin levels, blood pressure levels, and a healthier body mass index (BMI) when compared to inactive patients.

Aerobic exercise is associated with reductions in glycemia, while anaerobic exercise (sprinting, heavy weight lifting, and interval sports like hockey) is known to temporarily increase glucose levels. Both forms of exercise can produce hypoglycemia (severe low blood sugar) in late recovery, often when patients are sleeping. As such, patients with diabetes must consider which forms of exercise are best for them.

Is naturopathic medicine the answer for eating disorders?

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Thirty million Americans will struggle with disordered eating at some point in their lives. Nearly one million Canadians are living with a diagnosed eating disorder, and millions of others struggle with food and weight preoccupation.

These serious illnesses affect all kinds of individuals across the spectrum of gender, ethnicity, age, and socioeconomic status.

This month marks two observances to raise public awareness about the dangers of eating disorders. In the United States, the National Eating Disorders Association is spearheading National Eating Disorders Awareness Week from February 26th through March 4th. In Canada, the National Eating Disorder Information Centre is behind Eating Disorder Awareness Week from February 1st through February 7th.

Eating disorders, such as anorexia, bulimia, and binge eating, are complex and life threatening – they have the highest mortality rate of any mental illness. However, due to societal stigma, many eating disorders go undiagnosed or untreated.

Fighting Eating Disorders: Why Naturopathic Medicine May Be the Answer

McKesson Canada brings on new CEO

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McKesson Canada brings on new CEO

Domenic Pilla, the former CEO of Shoppers Drug Mart, has been named CEO of McKesson Canada. This move follows McKesson’s $2.9-billion acquisition of Rexall Health in late December.

 

Pilla was CEO of Shoppers from 2011 to 2015, and president of McKesson Canada from 2001 to 2011. In this new role, he assumes overall leadership responsibility for McKesson’s distribution and retail businesses in Canada, including Rexall Health.

 

In the future, Pilla is expected to appoint a new president of Rexall Health to provide day-to-day leadership for the banner.
“Domenic Pilla is uniquely qualified to lead our expanded portfolio in Canada based on his previous experience as president of Shoppers Drug Mart and McKesson Canada,” says Paul C. Julian, executive vice-president and group president of the McKesson Corporation. “He brings deep knowledge of both the wholesale and retail sides of the business, and a proven track record of delivering results.”

QR Pharma announces new Scientific Advisory Board

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QR Pharma announces new Scientific Advisory Board

QR Pharma Inc., a privately held Phase 2 biopharmaceutical company developing novel therapies for the treatment of Alzheimer’s, Parkinson’s and other neurodegenerative diseases, today announced the appointment of four world-class key opinion leaders to its Scientific Advisory Board (SAB). These new appointments join QR Pharma’s previous roster of impressive advisors in order to provide strategic leadership and direction to support the development of the breakthrough mechanism of action of Posiphen in neurodegenerative disease.

Posiphen is a first-in-class inhibitor of the neurotoxic aggregating proteins involved in the pathogenesis of conditions such as Alzheimer’s and Parkinson’s disease. Posiphen has been shown to reduce the expression of key neurodegenerative proteins including amyloid precursor protein, alpha synuclein and tau. This innovative mechanism of action could be applicable to several conditions in which multiple neurodegenerative proteins share responsibility for disease pathogenesis. Posiphen is currently being evaluated in a Phase 2A proof-of-concept/mechanism study for patients with early Alzheimer’s disease.

“We are thrilled to have attracted four world-class experts in the area of neurology to our team of scientific advisors,” stated Maria Maccecchini, Ph.D., President and CEO of QR Pharma. “They join at an exciting time for our company. Recent breakthrough discoveries regarding Posiphen’s mechanism of action suggest a first-in-class disease-modifying therapeutic with broad clinical application. The experience each of the new advisors brings to our team will be invaluable in realizing the full therapeutic potential of Posiphen in neurodegenerative disease.”

“Posiphen represents an opportunity to attack neurodegenerative disease at its roots,” commented Dr. Sidney Strickland, newChairman of the QR Pharma SAB and Professor of Neurology and Genetics at Rockefeller University. “Unlike other therapeutic modalities that only attack a single axis of neurodegenerative disease pathogenesis, Posiphen targets multiple disease-causing proteins. I look forward to working with the fellow members of the SAB and QR Pharma leadership to advance this promising therapeutic agent for patients suffering from debilitating neurodegenerative conditions.”

The four new scientific advisory board members are Wiliam Mobley, M.D., Ph.D.; Gregory Petsko, Ph.D.; Sidney Strickland, Ph.D.; and Rudolph Tanzi, Ph.D.

America’s #1 Enzyme Brand and Dr. Michael Murray Join Forces

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Xylitol Canada announces appointment of new team members

Enzymedica, Inc. is excited to announce that Dr. Michael Murray, author of over 30 books, including “The Encyclopedia of Natural Medicine,” and an individual who has been recently named “The Voice of Natural Medicine” by Nutrition Business Journal, has joined the company as Chief Science Officer.

 

According to Scott Sensenbrenner, CEO, “Dr. Murray is a true icon in the natural health movement and brings tremendous credibility, experience, and passion to our company.”

Dr. Murray will be critical to driving new innovations in product development for Enzymedica, as well as leading research efforts to create next generation formulas that will be groundbreaking for the industry.
In addition to his role with Enzymedica, Dr. Murray will be working closely with the Roskamp Institute in Sarasota, Fl. This non-profit organization is performing cutting edge research for organizations like the National Institutes of Health (NIH), Department of Defense (DOD) and the European Union (EU). Roskamp is renowned for their team’s research on Alzheimer’s disease, Gulf War Illness, and other complex diseases. Dr. Murray and the Institute will be developing better answers for improving brain health, the human microbiome and digestion.
Enzymedica’s strategic relationship with the Roskamp Institute gives it the resources and expertise critical for providing innovative, science-based natural products, furthering its contribution to digestive health. This close partnership is further demonstrated by Sensenbrenner, who serves on the Board of Directors of the Roskamp Institute.

Dr. Murray says, “I am thrilled to be part of the team at both Enzymedica and the Rosskamp Institute. It is a dream come true.”
Sensenbrenner and Dr. Murray previously worked together in the 1990s at Enzymatic Therapy, which was later acquired by the German company Dr. Wilmarr Schwabe Pharmaceuticals.
About Enzymedica:

Florida-based Enzymedica, Inc. was founded in 1998 to offer consumers targeted enzyme products, and only uses the highest quality vegetarian enzyme sources available. Digest™ and Digest Gold™ are the two top-selling digestive enzymes in the U.S. market according to SPINS, a market research and consulting firm for the Natural Products Industry. Enzymedica is a proud supporter of many green initiatives, including use of solar energy, recycled steel for its building and recycled paper for packing and shipping. Enzymedica also sponsors initiatives in autism, Safe Place and Rape Crisis Center (SPARCC) of Sarasota, and others.

About Dr. Murray:

Dr. Murray is one of the world’s leading authorities on natural medicine. He has published over 30 books featuring natural approaches to health. He is a graduate, former faculty member, and serves on the Board of Regents of Bastyr University in Seattle, Washington.

McKesson Canada and Sobeys National Pharmacy Group Announce New Long-Term Distribution Agreement

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Walmart-Visa dispute comes to an end

McKesson Canada and Sobeys National Pharmacy Group have announced the signing of a long-term distribution agreement that makes Lawton’s Drug Stores a primary distribution customer, enhancing McKesson Canada’s presence in Atlantic Canada. The agreement is effective February 1st, 2017.

 

Both McKesson Canada and Sobeys have a long history as trusted partners in patient care through quality products and services. This agreement leverages the strength of McKesson Canada as a national leader in pharmaceutical supply chain management and Sobeys’ position as an important destination for health and wellness needs.

 

“We are excited about our expanded relationship with Sobeys,” stated Paula Keays, President, McKesson Canada. “We have great confidence in the exceptional value we provide our customers and we appreciate the opportunity to work with Sobeys in delivering a broad range of pharmaceutical products and services to their customers.”

 

McKesson Canada and Sobeys have worked together for several years to provide a wide variety of prescriptions and health services to customers. Today’s announcement will allow for a consistent source of supply across all regions where Sobeys and Lawton Drugs serve customers including Atlantic Canada.

 

As a result of this announcement, McKesson Canada will leverage its existing Atlantic Canada distribution centers while adding resources where required and anticipates employment levels to be net neutral in the region.

Heartburn pills in pregnancy linked to childhood asthma

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A recent study from the University of Edinburgh found that children born to mothers prescribed medications to treat acid reflux during pregnancy have a higher risk of developing asthma.
While there is a potential link, researchers believe that mothers-to-be should follow existing guidelines and use the medication as prescribed.
Drugs called H2 receptor antagonists and proton pump inhibitors can help block acid reflux. They are considered safe to use during pregnancies.
Researchers reviewed eight previous studies involving more than 1.3 million children.
Professor Aziz Sheikh, Co-director of the Asthma UK Centre for Applied Research at the University of Edinburgh, said: “Our study reports an association between the onset of asthma in children and their mothers’ use of acid-suppressing medication during pregnancy. It is important to stress that this association does not prove that the medicines caused asthma in these children and further research is needed to better understand this link.”

French Study Prompts Re-evaluation of Titanium Dioxide

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The French minister of health, Marisol Touraine, and agriculture minister, Stéphane Le Foll, have submitted a request to reassess the safety of white food colouring titanium dioxide which has been approved by the government. Scientists say they have found that nanoparticples in the food additive can cross the intestinal barrier and pass into the bloodstream.

In September 2016, the European Food Safety Authority (EFSA) stated that current levels of dietary exposure to titanium dioxide posed no health concerns, although they have been unable to set an acceptable daily limit (ADI) due to lack of research.

The French food industry association ANIA have acknowledged the study was in its early stages and more research must be done to extrapolate the findings to humans.
The EFSA is calling for research to fill in the data gaps and will consider the relevance of the findings in due course.

Cronos supports German Legalization of Medical Cannabis

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PharmaCan Captial Corp., doing business as Cronos Group, is pleased to announce the German parliament’s expanded medical marijuana program. This landmark bill, which was unanimously votes by members of Germany’s parliament, legalizes the use of medical marijuana and implenets a policy to provide health insurance coverage for patients with an eligible prescription. The program and accompanying health insurance will cover dried cannabis flower as well as extracts.

Previously, beginning in October of 2016, Cronos, in partnership with Pedanios GmbH, supplied medical cannabis to German patients under the prior program. This restricted access to many patients suffering from serious chronic illness, and required patients to pay out of pocket for medication.

“It is a historic day for patients in Germany, and, as one of the only licensed distributors in the country, we are proud to be a part of it. We are at the forefront of compassionate care, using breakthrough treatments and best-in-class medications procured through our partnership with Cronos. Insurance coverage for medical cannabis in Germany now clears the way for us to extend our joint venture across the EU as the regulatory environment continues to evolve,” says Patrick Hoffmann, Executive Partner of Pedanios.

Cronos expanded its supply agreement in December 2016 to become Pedanios’ exclusive North American supplier of cannabis products distributed within the European Union and Switzerland.

“The approval of this landmark bill is a watershed moment for German patients, Cronos, and cannabis advocates around the world. It marks a significant development in our shared vision with Pedanios to offer patients access to an insurance-covered alternative. Through our agreement with Pedanios, we are excited to offer co-branded products not only within in Germany, but also throughout the European Union in the near future,” says Mike Gorenstein, Cronos Group’s CEO.