Doctor’s Data, Inc. (DDI) has developed a Methylation Profile to report on plasma concentrations of key amino acids and intermediary metabolites in order to permit the evaluation of disorders in methionine metabolism. Potential consequences of untreated aberrant methionine metabolism include abnormal neurotransmitter metabolism and neuropsychiatric disorders, nitric oxide dyshomeostasis, global under-methylation/synthesis/ repair of DNA, immune dysregulation, cancer, cardiovascular disease, congenital heart disease/birth defects, neurodegenerative disease, impaired endogenous detoxification and increased risk for Down syndrome. Improvements in disordered methionine metabolism may be accomplished through nutritional intervention guided by the DDI Methylation Profile.
